Selective white matter abnormalities in a novel rat model of vascular dementia
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چکیده
منابع مشابه
Selective white matter abnormalities in a novel rat model of vascular dementia.
Rats subjected to bilateral common carotid artery (CCA) occlusion or 2-vessel occlusion (2VO) have been used as animal models of subcortical ischemic vascular dementia. However, this model possesses an inherent limitation in that cerebral blood flow (CBF) drops too sharply and substantially after ligation of CCAs. To circumvent such hypoxic-ischemic conditions, we tested implantation of the ame...
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ژورنال
عنوان ژورنال: Neurobiology of Aging
سال: 2012
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2011.10.033